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Pharmacological inhibition of PI K induces apoptosis
2019-04-15

Pharmacological inhibition of PI3Kα induces apoptosis of CLL butein in vitro [5,18], and inhibits CLL migration towards CXCL12 [5]. The PI3Kα/δ inhibitor copanlisib induces significantly greater apoptosis of CLL cells compared to idelalisib (IC50 of 450nM and >10μM, respectively) in vitro and is cu
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The principal difference between BrS and ERS is
2019-04-11

The principal difference between BrS and ERS is related to the region of the ventricle most affected. Epicardial mapping studies in BrS patients report accentuated J waves and fragmented and/or late potentials in the epicardial region of the RVOT [129–131], whereas in ERS only accentuated J waves, p
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2018-07-29
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